Download Dynamics of Cell Division (Frontiers in Molecular Biology) by Sharyn Endow, David Glover PDF

By Sharyn Endow, David Glover

ISBN-10: 0199636826

ISBN-13: 9780199636822

ISBN-10: 0585483884

ISBN-13: 9780585483887

This quantity makes a speciality of the structural elements of cellphone department, starting from nuclear envelope breakdown to cytokinesis and partitioning of the cytoplasm. It examines spindle meeting and chromosome habit in mitosis and meiosis, centromere and kinetochore constitution and rules, telomeres, the function of centrosomes, and mechanisms through which total legislation is accomplished. Written as a significant other quantity to mobile Cycle regulate, this booklet offers an up to date account of advancements during this fascinating sector of mobilephone biology.

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Extra info for Dynamics of Cell Division (Frontiers in Molecular Biology)

Sample text

3 Tension is monitored by the spindle assembly checkpoint Micromanipulation studies in spermatocytes of praying mantids indicate that the spindle assembly checkpoint monitors tension on the kinetochores (Fig. 6) (164). The spermatocytes of praying mantids manage an XXY sex chromosome constitution by forming a trivalent in which the two X chromosomes pair and segregate from the single Y chromosome. Occasionally the trivalent breaks down because an X chromosome prematurely detaches from the Y, generating an unpaired X.

1993) p21 is a universal inhibitor of cyclin kinases. Nature, 366, 701. 36. Harper, J. , Adami, G. , and Elledge, S. J. (1993) The p21 Cdkinteracting protein Cipl is a potent inhibitor of G! cyclin-dependent kinases. Cell, 75, 805. 37. , Hannon, G. , and Beach, D. (1994) p21-containing cyclin kinases exist in both active and inactive states. , 8,1750. 38. Toyoshirna, H. and Hunter, T. (1994) p27, a novel inhibitor of G: cyclin-Cdk protein kinase activity, is related to p21. Cell, 78,67. 39. Polyak, K.

9. Weinert, T. A. and Hartwell, L. H. (1990) Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts post-translationally in cell cycle arrest afer DNA damage. Mol. Cell. , 10, 6554. 10. , Labbe, J. C, and Nigg, E. A. (1990) In vitro disassembly of the nuclear lamina and M-phase specific phosphorylation of lamins by cdc2 kinase. Cell, 61,591. 11. , and Karsenti, E. (1990) Regulation of microtubule dynamics by cdc2 protein kinase in cell-free extracts of Xenopus eggs.

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Dynamics of Cell Division (Frontiers in Molecular Biology) by Sharyn Endow, David Glover


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