Download Crohn's Disease: Current Concepts by Arumugam Rajesh, Rakesh Sinha (eds.) PDF

By Arumugam Rajesh, Rakesh Sinha (eds.)

ISBN-10: 3319019120

ISBN-13: 9783319019123

ISBN-10: 3319019139

ISBN-13: 9783319019130

​This booklet will contain a multimodality strategy towards inflammatory bowel ailments. brand new imaging methodologies can be defined in addition to their strengths and weaknesses that would assist in delivering a rational diagnostic approach for medical, surgical and aid groups operating with those sufferers. Advances in clinical and surgical procedure will be specified and those will be priceless to readers and execs prepared to enforce those options of their personal medical practice.

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2011;106(1):110–9. 9. Geboes K, Ectors N, D’Haens G, Rutgeerts P. Is ileoscopy with biopsy worthwhile in patients presenting with symptoms of inflammatory bowel disease? Am J Gastroenterol. 1998;93(2):201–6. 10. Schmitz-Moormann P, Pittner PM, Malchow H, Brandes JW. The granuloma in Crohn’s disease. A bioptical study. Pathol Res Pract. 1984;178(5):467–76. 21 11. Jenkins D, Balsitis M, Gallivan S, Dixon MF, Gilmour HM, Shepherd NA, et al. Guidelines for the initial biopsy diagnosis of suspected chronic idiopathic inflammatory bowel disease.

This is particularly relevant as recently there has been a shift in the treatment paradigm from clinical response (resolution of symptoms) to biological response (resolution of serological or faecal biomarkers) and especially mucosal healing. The latter has been associated with hard endpoints in patients with CD, such as prolonged remission, fewer hospitalizations and surgeries [30–32]. Finally, VCE can be utilized to detect post-surgical recurrence in patients who have undergone small bowel resection.

It has to be acknowledged that diagnostic yield is not equivalent to a positive diagnosis and, therefore, although capsule endoscopy has very high sensitivity for small bowel lesions, the significance of all these abnormalities is unclear. Overall, most studies suggest that VCE has superior sensitivity for the detection of small bowel CD compared with other radiologic studies, with variable specificity. In contrast, cross-sectional imaging studies provide useful information regarding mural and extra-mural pathology such as fistulas, abscesses, masses or lymphadenopathy.

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Crohn's Disease: Current Concepts by Arumugam Rajesh, Rakesh Sinha (eds.)


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