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By I. Chaikovsky, N. Sydorova

ISBN-10: 9535102389

ISBN-13: 9789535102380

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123 pp. , S. (1979). Analysis of Probability as an Aid in the Clinical Diagnosis of Coronary-Artery Disease. N Engl J Med (1986) Vol. 1350-1358 Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol I Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation and treatment of high blood cholesterol in adults (Adult Treatment Panel III). 2001. JAMA (2001) Vol. 285 pp. M. et al. (2006). An assessment of incremental coronary risk prediction using C-reactive protein and other novel risk markers: the Atherosclerosis Risk in Communities study.

The mitochondria-target agents include mainly coenzyme Q10 (CoQ) and lipoic acid. CoQ levels have been shown to be lower in hypertensive patients. CoQ may reduce mitochondrial O2•- production and reduce lipid peroxidation in plasma; CoQ supplementation was also demonstrated to reduce blood pressure. The potential beneficial effects of lipoic acid supplementation is given because it may improve coupling of NOS and has anti-inflammatory actions (Kizhakekuttu & Widlansky, 2010). 5. Conclusion Throughout this chapter we have seen the numerous connections between heart disease, associated diseases and oxidative.

045), and the interaction effect of the two genes on serum cholesterol level, attenuated de risk of CHD. The concept of gene-gene interaction can thus be extended to the existence of protective and/or suppressive genetic variants, which when identified could make an important contribution to preventing further development of CHD or improving its clinical course. Gene-environment interaction implies that, in combination, the effect of the genotype and the environmental factor is greater than the additive effect of each.

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Coronary Artery Diseases by I. Chaikovsky, N. Sydorova

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