Download Cellular Peptidases in Immune Functions and Diseases 2 by Uwe Lendeckel, Thilo Kähne, Dagmar Riemann, Klus Neubert, PDF

By Uwe Lendeckel, Thilo Kähne, Dagmar Riemann, Klus Neubert, Marco Arndt, Dirk Reinhold (auth.), Jürgen Langner, Siegfried Ansorge (eds.)

ISBN-10: 0306463830

ISBN-13: 9780306463839

ISBN-10: 0306468263

ISBN-13: 9780306468261

Of the various detailed roles performed through proteolytic enzymes in immune reactions, this ebook addresses diverse points of membrane peptidases, sign transduction through ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and law of membrane peptidases in vivo and in vitro. a couple of newly found peptidases (including cathepsin F, W and X, carboxypeptidase X, attractin) are defined, with precise emphasis given to the position of peptidases in immune and safeguard reactions and within the pathogenesis of inflammatory and different illnesses, together with rheumatoid arthritis, pancreatitis, a number of sclerosis, Alzheimer's affliction and tumours of assorted origins. the point of interest at the involvement of a variety of proteolytic enzymes in immune reactions and ailments is a distinct function of this multifaceted paintings , which mixes biochemical, immunological and medical learn stories with literary reports of the sector.

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1998, Aminopeptidase N in sera of healthy subjects is a different N-terminal processed derivative from the one obtained from maternal serum. Mol. Gen. Metab. 63: 289-294. , 1989, Amino acid sequence deduced from a rat kidney cDNA suggests it encodes Zn-peptidase aminopeptidase N. J. Biol. Chem. 264: 5480-5487. , 1993, Complete sequence of rabbit kidney aminopeptidase N and mRNA localization in rabbit kidney by in situ hybridization. Biochem. Cell. Biol. 71: 278-287. , and Holmes, K. , 1992, Human aminopeptidase N is a receptor for human coronavinis 229E.

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Lett. 46: 189-193. , 1998, Early phosphorylation events induced by DPIV/CD26-specific inhibitors. Cell. Immunol. 189: 60-66. , 1999, Dipeptidyl peptidase IV: A cell surface peptidase involved in regulating T cell growth (Review). Int. J. Mol. Med. 4: 3-15. , 1998, Regulation of the expression of aminopeptidase A, aminopeptidase N/CD13 and dipeptidyl peptidase IV/CD26 in renal cell carcinomas cells and renal tubular epithelial cells by cytokines and cAMP-increasing mediators. Clin. Exp. Immunol.

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Cellular Peptidases in Immune Functions and Diseases 2 by Uwe Lendeckel, Thilo Kähne, Dagmar Riemann, Klus Neubert, Marco Arndt, Dirk Reinhold (auth.), Jürgen Langner, Siegfried Ansorge (eds.)


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