Download Cascade Biocatalysis Integrating Stereoselective and by Sergio Riva, Wolf-Dieter Fessner PDF

By Sergio Riva, Wolf-Dieter Fessner

ISBN-10: 3527335226

ISBN-13: 9783527335220

This prepared reference provides environmentally pleasant and stereoselective equipment of recent biocatalysis. The skilled and popular workforce of editors have amassed most sensible foreign authors for this e-book. They disguise such rising subject matters as chemoenzymatic equipment and multistep enzymatic reactions, whereas displaying how those novel tools and ideas can be utilized for functional purposes. Multidisciplinary subject matters, together with directed evolution, dynamic kinetic answer, and continuous-flow method also are discussed.

From the contents:
* Directed Evolution of Ligninolytic Oxidoreductases: from useful Expression to Stabilization and Beyond
* New developments within the In Situ Enzymatic Recycling of NAD(P)(H) Cofactors
* Monooxygenase-Catalyzed Redox Cascade Biotransformations
* Biocatalytic Redox Cascades related to w-Transaminases
* Multi-Enzyme platforms and Cascade Reactions related to Cytochrome P450 Monooxygenases
* Chemo-Enzymatic Cascade Reactions for the Synthesis of Glycoconjugates
* Synergies of Chemistry and Biochemistry for the creation of Beta-Amino Acids
* Racemizable Acyl Donors for Enzymatic Dynamic Kinetic Resolution
* Stereoselective Hydrolase-Catalyzed approaches in Continuous-Flow Mode
* views on Multienzyme technique Technology
* Nitrile changing Enzymes fascinated by normal and artificial Cascade Reactions
* Mining Genomes for Nitrilases
* Key-Study at the Kinetic elements of the In-Situ NHase/AMase Cascade method of M. imperiale Resting Cells for Nitrile Bioconversion
* Enzymatic Stereoselective Synthesis of Beta-Amino Acids
* New purposes of Transketolase: Cascade Reactions for Assay Development
* Aldolases as Catalyst for the Synthesis of Carbohydrates and Analogs
* Enzymatic iteration of Sialoconjugate Diversity
* Methyltransferases in Biocatalysis
* Chemoenzymatic Multistep One-Pot Processes

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Additional info for Cascade Biocatalysis Integrating Stereoselective and Environmentally Friendly Reactions

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Agricultural wastes) in the production of second-generation biofuels (bioethanol, biobutanol) or the manufacture of new cellulose-derived and lignin-derived value-added products. • The organic synthesis of drugs and antibiotics, cosmetics and complex polymers, and building blocks. • In nanobiotechnology as (i) biosensors (for phenols, oxygen, hydroperoxides, azides, morphine, codeine, catecholamines, or flavonoids) for clinical and environmental applications; and (ii) biofuel cells for biomedical applications.

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Nat. , 17, 379–384. , and Larsen, S. (2003) The structure of a mutant enzyme of Coprinus cinereus peroxidase provides an understanding of its increased thermostability. , Sect. D: Biol. , 59, 997–1003. H. (2001) Functional expression and stabilization of horseradish peroxidase by directed evolution in Saccharomyces cerevisiae. Biotechnol. , 76, 99–107. C. H. (2012) Directed evolution of the peroxidase activity of a novo-designed protein. Protein Eng. Des. , 25 (9), 445–451. , and Takahashi, H. (2003) Improvement of H2 O2 stability of manganese peroxidase by combinatorial mutagenesis and high-throughput screening using in vitro expression with protein disulfide isomerase.

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Cascade Biocatalysis Integrating Stereoselective and Environmentally Friendly Reactions by Sergio Riva, Wolf-Dieter Fessner


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