By P. Narayanan
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A pragmatic undergraduate textbook for maths-shy biology scholars exhibiting how uncomplicated maths unearths very important insights.
This publication introduces the reader to the kinetic research of quite a lot of organic techniques on the molecular point. It exhibits that a similar process can be utilized to unravel the variety of steps for a variety of platforms together with enzyme reactions, muscle contraction, visible belief, and ligand binding.
Dieses Buch ist als EinfUhrung in die Theoretische Okologie gedacht. Den Begriff "okologisches Modell" habe ich im Titel absichtlich vermieden, denn hierzu ziihlen ganz verschiedene Methoden der mathematischen Beschreibung von okologischen V orgiingen. Ziel einer Theorie ist es, ein Verstandnis fUr die Vor gange und funktionellen Zusammenhange eines Fachgebietes zu erlangen.
Extra info for Bioinformatics: A primer
Typically a peptide consists of less than 50 amino acids while a protein has greater than 50 amino acids. Fig. 4 Formation of Polypeptides from Amino Acids via Peptide (C–N) bonds Operationally, the structural and functional features and protein complexes are addressed at four levels of hierarchical structural organization (1) primary structure, (2) secondary structure, (3) tertiary structure and (4) quaternary structure. 1 The Primary Structure (1°-Structure) The linear number and order of the amino acids present in a peptide or protein constitutes the primary structure (1°-structure).
1 – 3 kb). Microchip electrophoresis is an electrophoretic method that has considerable impact in DNA separations, in large part because microchip electrophoresis offers some clear advantages over slab gel electrophoresis for automation, speed, and quantitative capability. 2 Column Electrophoresis Both slab gel and capillary gel (and free-solution) matrices can be employed to separate nucleic acids and proteins. In order to accomplish sizing, a sieving matrix is prepared and loaded either between two glass plates (slab gel), or into glass capillaries.
High Performance Liquid Chromatographic (HPLC) methods are aimed at increasing the efficiency of liquid chromatography to a high level of sensitivity (10–12 g/L). Advent of HPLC has resulted in tremendous progress in the separation of a wide variety of inorganic and organic compounds. Reversedphase HPLC (based on the hydrophobicity of compounds) has become the workhorse for purification and characterization of molecules of biological importance. Denaturing high-performance liquid chromatography (dHPLC) is used in single nucleotide polymorphism (SNP)-detection methods, based on discrimination between perfect and mismatched hybridization, measures melting temperatures.
Bioinformatics: A primer by P. Narayanan