By Martin Röcken, Tilo Biedermann (auth.), Michael Hertl MD (eds.)
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Additional info for Autoimmune Diseases of the Skin: Pathogenesis, Diagnosis, Management
1995; Sanchez-Guerrero et al. 1995b; Park et al. 1997; Edworthy et al. 1998; Nyren et al. 1998). The relative risks in Tables 8-11 are for CTD if not indicated otherwise. Results for the different specified CTD (mostly SSe) are given in the text as far as available. The first report, whose results could be compared with other studies came from Spiera (1988) of New York City, who reported that five of his 113 new female SSe patients had breast implants as had one of his 286 RA patients, and none of his patients with SLE or polymyositis.
In: Black CM, Myers AR (eds) Systemic Sclerosis (Scleroderma). Gower, New York, p 78 Ball C, Sackett D, Phillips B, Haynes B, Straus S (1999) Levels of evidence and grades of recommendations Bastuji-Garin S, Joly P, Picard-Dahan C, Bernard P, Vaillant L, Pauwels C, Salagnac V, Lok C, Roujeau JC (1996) Drugs associated with bullous pemphigoid. A case-control study. Arch Dermatol 132: 272-276 Bernard P, Vaillant J, Labeille B, Bedane C, Arbeille B, Denoeux JP et al. (1995) Incidence and distribution of subepidermal bullous skin diseases in three french regions.
This seems to be more efficient and better tolerated than any of the previously described immmunosuppressive agents (Feldmann et al. 1996). However, therapies based on anti-TNF-antibodies inhibit any type of immune response and therefore harbor a series of risks for patients with acute or chronic infections. Among autoimmune skin diseases, psoriasis has been shown to improve under anti-TNF-therapies (Mease et al. 2000). This is an important prove of principle. However, other highly effective but less invasive therapies are available for psoriasis.
Autoimmune Diseases of the Skin: Pathogenesis, Diagnosis, Management by Martin Röcken, Tilo Biedermann (auth.), Michael Hertl MD (eds.)