By Sumaira Z. Aasi, David J. Leffell, Rossitza Z. Lazova
Mohs surgical procedure is microscopically managed surgical procedure used to regard universal sorts of dermis melanoma and allows the elimination of a dermis melanoma with a truly slender surgical margin and a excessive remedy price. in spite of the fact that, for these concerned with the Mohs technique, it really is serious to appreciate the optimum instruction and interpretation of frozen sections.
Complete with 1000s of excessive answer figures, Atlas of sensible Mohs Histopathology is written by means of prime specialists within the box and discusses every thing from basic epidermis histology and infrequent tumors to pitfalls and incidental findings. Dermatologic surgeons, Mohs cutaneous surgeons, dermatopathologists and pathologists alike will locate this e-book to be a accomplished and fundamental reference.
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Extra resources for Atlas of Practical Mohs Histopathology
There is a variable irregularly scattered lymphocytic inflammatory infiltrate associated with the neoplastic stroma in a perivascular and perineural distribution. 10. Perineural invasion is sometimes present. Z. 1007/978-1-4614-5161-7_4, © Springer Science+Business Media New York 2013 47 48 4 Infiltrative Basal Cell Carcinoma Histopathologic Differential Diagnosis Syringoma 1. 2. 3. 4. 5. Well-demarcated tumor limited to the upper dermis. Small epithelial aggregates with rounded, coma-like, or tadpole shapes, as well as elongated strands of epithelial cells.
Higher magnifications sometimes might be misleading and, as in this case, might lead the surgeon into making an erroneous diagnosis of Merkel cell carcinoma based on cytologic features alone 3 a b Basal Cell Carcinoma Basal Cell Carcinoma Fig. 10 (continued) 35 c 36 Fig. 11 Basal cell carcinoma: (a) This subtle basal cell carcinoma (arrow) is hidden among sebaceous glands and hair follicles. It can be easily overlooked because of its resemblance to a distorted hair follicle. A hair follicle at this level in the dermis would display organized and complex morphology as present in the surrounding folliculosebaceous units.
This case illustrates the utility of reviewing the original biopsies of tumors prior to Mohs surgery 39 a b c 40 Fig. 15 Basal cell carcinoma: (a) Scanning magnification shows focal areas of dense inflammation in the superficial and mid dermis on the left side of this photomicrograph. Arrows point to two small neoplastic aggregates that can be easily missed via a cursory examination of the specimen. (b) Neoplastic aggregates are more obvious on higher magnification (arrows) 3 a b Basal Cell Carcinoma Basal Cell Carcinoma Fig.
Atlas of Practical Mohs Histopathology by Sumaira Z. Aasi, David J. Leffell, Rossitza Z. Lazova