Download Apoptosis, Cell Signaling, and Human Diseases: Molecular by Rakesh Srivastava PDF

By Rakesh Srivastava

ISBN-10: 1588296776

ISBN-13: 9781588296771

ISBN-10: 1588298825

ISBN-13: 9781588298829

ISBN-10: 1597451991

ISBN-13: 9781597451994

(for either volumes) Apoptosis, mobile Signaling, and Human illnesses: Molecular Mechanisms, Volumes 1 & 2, current a concise synthesis of contemporary advancements within the realizing of either phone survival and apoptotic pathways. specific recognition is given to apoptosis in human illnesses, equivalent to various different types of melanoma and neurodegenerative ailments. those finished volumes combine the main cutting edge and present findings from numerous similar disciplines of clinical learn, together with pathology, genetics, virology, mobilephone biology, immunology, and molecular biology. quantity 1 is split into sections: "Malignant Transformation and Metastasis" and "Molecular foundation of sickness Therapy." quantity 2 follows the same constitution and is split into sections entitled "Kinases and Phosphate" and "Molecular foundation of telephone Death." all the participants are on the leading edge of clinical discovery, and the experiences they current systemically learn the main fascinating and leading edge features in their specific components of workmanship. Researchers will locate those volumes of significant profit as they look for novel and more suitable remedies for human ailments.

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Additional resources for Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms

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Keryer G, Yassenko M, Labbe JC, Castro A, Lohmann SM, Evain-Brion D, et al. Mitosisspecific phosphorylation and subcellular redistribution of the RIIalpha regulatory subunit of cAMP-dependent protein kinase. J Biol Chem 1998;273:34,594–34,602. 38. Carlson CR, Witczak O, Vossebein L, et al. CDK1-mediated phosphorylation of the RIIalpha regulatory subunit of PKA works as a molecular switch that promotes dissociation of RIIalpha from centrosomes at mitosis. J Cell Sci 2001;114:3243–3254. 39. Kondrashin AA, Nesterova MV, Cho-Chung YS.

Kuret J, Johnson KE, Nicolette C, Zoller MJ. Mutagenesis of the regulatory subunit of yeast cAMP-dependent protein kinase: Isolation of site-directed mutants with altered binding affinity for catalytic subunit. J Biol Chem 1988;263:9149–9154. 98. Nesterova MV, Yokozaki H, McDuffie L, Cho-Chung YS. Overexpression of RIIG regulatory subunit of protein kinase A in human colon carcinoma cell induces growth arrest and phenotypic changes that are abolished by site-directed mutation of RIIG. Eur J Biochem 1996;235:486–494.

Solberg R, Tasken K, Keiserud A, Jahnsen T. Molecular cloning, cDNA structure and tissue-specific expression of the human regulatory subunit RI beta of cAMP-dependent protein kinases. Biochem Biophys Res Commun 1991;176:166–172. 13. Scott JD, Glaccum MB, Zoller MJ, Uhler MD, Helfman DM, McKnight GS, et al. The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain. Proc Natl Acad Sci USA 1987;84:5192–5196. 14. Øyen O, Myklebust F, Scott JD, Hansson V, Jahnsen T.

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Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms by Rakesh Srivastava

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