By Abraham Fisher, Israel Hanin, Werner Poewe, Manfred Windisch
Read Online or Download Alzheimer's and Parkinson's Diseases: Progress and New Perspectives: 8th International Conference Ad pd, Salzburg, March 2007: Abstracts (Neuro-Degenerative Diseases) PDF
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Additional resources for Alzheimer's and Parkinson's Diseases: Progress and New Perspectives: 8th International Conference Ad pd, Salzburg, March 2007: Abstracts (Neuro-Degenerative Diseases)
The changes in regulated intramembrane proteolysis of p75NTR elucidated in these studies may have an effect on the balance between TrkA and p75NTR receptors and their respective signalling pathways. This balance is vital in the maintenance of healthy cholinergic neurons. Thus alterations in cleavage of p75NTR may influence this equilibrium in disease states such as Alzheimer’s disease. PC12 cells were stably transfected with familial mutations M146V, A246E and deltaE9 and wild type presenilin 1.
2004 Biochemistry (Moscow) 69(7):705-19. S. 2005 Neurochem. Res. 30(11):1443-51. 85 Audit of Dementia and Non-Insulin Dependent Diabetes - Are We Jumping the Gun? R. Potluri, A. Natalwala Medical School, University of Birmingham, UK Background-Alzheimer’s disease (AD) and Vascular Dementia (VD) lead to cognitive decline via different aetiologies. Studies show that Non-Insulin Dependent Diabetes Mellitus (NIDDM) patients are at higher risk of AD than controls. NIDDM patients are also prone to cardiovascular co-morbidities, predisposing them to VD.
Design & Methods: We analyzed all available clinical, radiologic, genetic, and pathologic data in all affected individuals in the F147 kindred evaluated and followed by the authors. Results: We previously evaluated a male executive who at age 60 began experiencing frontotemporal dementia and postural tremor. Neuropsychological testing demonstrated impaired learning, memory, and executive functions. MRI revealed left greater than right anterior temporal and bifrontal atrophy as well as diffuse white matter hyperintensities.
Alzheimer's and Parkinson's Diseases: Progress and New Perspectives: 8th International Conference Ad pd, Salzburg, March 2007: Abstracts (Neuro-Degenerative Diseases) by Abraham Fisher, Israel Hanin, Werner Poewe, Manfred Windisch