Download Achalasia: Diagnosis and Treatment by P. Marco Fisichella, Fernando A. M. Herbella, Marco G. Patti PDF

By P. Marco Fisichella, Fernando A. M. Herbella, Marco G. Patti

ISBN-10: 3319135686

ISBN-13: 9783319135687

ISBN-10: 3319135694

ISBN-13: 9783319135694

every one bankruptcy describes a truly particular point of Achalasia via its recognized specialist. present diagnostic and administration techniques of Achalasia, in addition to the simplified operative methods with proper technical issues, are defined for the explicit goal audience.

The remedy of Achalasia is advanced and customarily played in really expert tertiary-care centres. The Editors' major objective is to render this ailment extra comprehensible and obtainable to citizens, fellows, and experts in either the surgical disciplines (general surgical procedure and thoracic surgical procedure) and in gastroenterology.

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Extra info for Achalasia: Diagnosis and Treatment

Sample text

A unit for these preparations is defined as medial lethal dose in mice, but FDA emphasizes that these various preparations and activity assays are not equivalent, and the doses should not be considered equivalent between the various forms of BoNT. Mechanism of Action These various BoNT serotypes inhibit acetylcholine release at the neuromuscular junction by binding to neurons via the Heavy Chain, entering the cell by receptor-mediated endocytosis, then translocating the Light Chain into the cytoplasm via an ATP- and pH-dependent mechanism where it acts as a zinc-dependent endoprotease to cleave a specific protein essential for neurotransmitter release (Fig.

Kahrilas PJ, Kishk SM, Helm JF, et al. Comparison of pseudoachalasia and achalasia. Am J Med. 1987; 82:439–46. 10. Rozman Jr RW, Achkar E. Features distinguishing secondary achalasia from primary achalasia. Am J Gastroenterol. 1990;85:1327–30. 11. Moonka R, Patti MG, Feo CV, Arcerito M, De Pinto M, Horgan S, Pellegrini CA. Clinical presentation and evaluation of malignant pseudoachalasia. J Gastrointest Surg. 1999;3:456–61. 12. Howard PJ, Maher L, Pryde A, et al. Five year prospective study of the incidence, clinical features, and diagnosis of achalasia in Edinburgh.

Eckardt VF, Stauf B, Bernhard G. Chest pain in achalasia: patient characteristics and clinical course. Gastroenterology. 1999;116(6):1300–4. 5. Perretta S, Fisichella PM, Galvani C, Gorodner MV, Way LW, Patti MG. Achalasia and chest pain: effect of laparoscopic Heller myotomy. J Gastrointest Surg. 2003;7:595–8. 6. Eckardt VF. Clinical presentations and complications of achalasia. Gastrointest Endosc Clin N Am. 2001; 11:281–92. 7. Sandler RS, Bozymski EM, Orlando RC. Failure of clinical criteria to distinguish between primary achalasia and achalasia secondary to tumor.

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Achalasia: Diagnosis and Treatment by P. Marco Fisichella, Fernando A. M. Herbella, Marco G. Patti


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